Advancing genetic research to identify mutations that cause sudden cardiac death and improve patient outcomes.
Sudden cardiac death refers to an unexpected death caused by a sudden loss of heart function. Sudden cardiac death is often triggered by dangerous genetic mutations. While identifying these mutations is essential for prediction and prevention, understanding the underlying mechanisms remains limited. Sudden cardiac death is a major health concern. Each incident costs society around $3 million, meaning that preventing 10% of these deaths in young Australians could save approximately $40 million annually.
The Victor Chang Cardiac Research Institute has investigated variants in genes that encode ion channels, which are the proteins that control the movement of electrical signals between cells. The majority of genetic disorders that lead to an increased risk of sudden cardiac arrest are caused by these mutations. By further identifying and understanding genetic mutations, the research team aims to improve the prediction of sudden cardiac death and ultimately save lives.
Hearts and Minds measures its impact across six core categories as developed by the Association of Australian Medical Research Institutes. Key highlights include:
The program aims to:
This project is crucial for advancing the prediction and prevention of sudden cardiac death. By identifying and understanding genetic mutations, this project aims to save lives, reduce healthcare costs and improve the quality of life for individuals with inherited heart disorders.
Funding support from Hearts and Minds Investments. This content was last updated in July 2024, for further information and updates, visit Victor Chang Cardiac Research Institute.